Anti-AKT1 monoclonal antibody (DMABT-H12610)
Mouse Anti-Human AKT1 monoclonal antibody for WB, IHC, IF, IP, sELISA, ELISA
Datasheet
Bring this labeled antibody directly to your bench!
Specifications
Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3F22
Species Reactivity
Human, Mouse, Rat
Immunogen
AKT1 (AAH00479.1,2a.a. ~ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Target
Alternative Names
AKT1; v-akt murine thymoma viral oncogene homolog 1; RAC-alpha serine/threonine-protein kinase; AKT; PKB; PRKBA
Entrez Gene ID
UniProt ID
Product Background
Pathway
AKT phosphorylates targets in the cytosol, organism-specific biosystem; AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem;
Citations
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References
Xu, DZ; Yao, YX; et al. Regulation of PTEN Stability and Activity by Plk3. JOURNAL OF BIOLOGICAL CHEMISTRY 285:39935-39942(2010).
Yuan, ZQ; Sun, M; et al. Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer. ONCOGENE 19:2324-2330(2000).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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