Anti-AKT1 monoclonal antibody (DMABT-H12610)
Mouse Anti-Human AKT1 monoclonal antibody for WB, IHC, IF, IP, sELISA, ELISA
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3F22
Species Reactivity
Human, Mouse, Rat
Immunogen
AKT1 (AAH00479.1,2a.a. ~ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Target
Alternative Names
AKT1; v-akt murine thymoma viral oncogene homolog 1; RAC-alpha serine/threonine-protein kinase; AKT; PKB; PRKBA
Entrez Gene ID
UniProt ID
Product Background
Pathway
AKT phosphorylates targets in the cytosol, organism-specific biosystem; AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem;
Citations
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References
Hussain, T; Scaife, L; et al. 14-3-3 proteins, tBID, Akt1 and FAKY397 may be predictive biomarkers of response to neoadjuvant chemotherapy in oestrogen receptor positive breast cancer as revealed by combined antibody microarray and 2d-Page/Maldi/Tof/Tof/Ms proteomics. BRITISH JOURNAL OF SURGERY 101:21-21(2014).
Le, XF; Mao, WQ; et al. Dasatinib Induces Autophagic Cell Death in Human Ovarian Cancer. CANCER 116:4980-4990(2010).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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