Anti-AGTR1 polyclonal antibody (DPABH-16623)

Goat anti-Human AGTR1 (aa 227-240) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide: C-EIQKNKPRNDDIFK, corresponding to internal sequence amino acids 227-240 of Human Angiotensin II Type 1 Receptor
Conjugate
Unconjugated

Applications


Application Notes
Peptide ELISA: antibody detection limit dilution 1:32,000. WB: Use at a concentration of 0.3 - 1 μg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 41 kDa).
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
AGTR1; angiotensin II receptor, type 1; AT1; AG2S; AT1B; AT1R
Entrez Gene ID
UniProt ID

Product Background


Pathway
ACE Inhibitor Pathway; Adrenergic signaling in cardiomyocytes; Arf6 signaling events; Calcium signaling pathway

Citations


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References


Sun, YX; Liao, YH; et al. Influence of autoantibodies against AT(1) receptor and AGTR1 polymorphisms on candesartan-based antihypertensive regimen Results from the Study of Optimal Treatment in Hypertensive Patients with Anti-AT(1)-Receptor Autoantibodies trial. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION 8:21-27(2014).
Rhodes, DR; Ateeq, B; et al. AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106:10284-10289(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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