Anti-AGTR1 monoclonal antibody (DCABH-10305)

Mouse anti-Human AGTR1 monoclonal antibody for IHC-P, ELISA, IP, WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2F21-2B0
Species Reactivity
Human
Immunogen
Fusion protein: LNPL FYGFL GKKFK RYFL QLLKYI PPK AKSHSNL ST KMSTLSYR P SDNVSSSTK KPAPCF, corresponding to C terminal amino acids 297-356 of Human Angiotensin II Type 1 Receptor
Conjugate
Unconjugated

Target


Alternative Names
AGTR1A; angiotensin II receptor, type 1a; type-1A angiotensin II receptor; angiotensin receptor 1a; angiotensin II type-1A receptor; vascular type-1 angiotensin II receptor
Entrez Gene ID
UniProt ID

Product Background


Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;

Citations


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References


Sun, YX; Liao, YH; et al. Influence of autoantibodies against AT(1) receptor and AGTR1 polymorphisms on candesartan-based antihypertensive regimen Results from the Study of Optimal Treatment in Hypertensive Patients with Anti-AT(1)-Receptor Autoantibodies trial. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION 8:21-27(2014).
Rhodes, DR; Ateeq, B; et al. AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106:10284-10289(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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