Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 353-382 of Human alpha 2C Adrenergic Receptor (NP_000674.2).
The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
Pathway
Adrenaline signalling through Alpha-2 adrenergic receptor; Adrenoceptors; Class A/1 (Rhodopsin-like receptors); G alpha (z) signalling events
Citations
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