This gene encodes a protein which is a member of the calcitonin-related hormones. The encoded protein is involved in maintaining homeostasis in many tissues, acting via CRLR/RAMP receptor (calcitonin receptor-like receptor/receptor activity-modifying protein) complexes. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Pathway
Calcitonin-like ligand receptors; Class B/2 (Secretin family receptors); G alpha (s) signalling events; GPCR downstream signaling; GPCR ligand binding; Signal Transduction; Signaling by GPCR.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Watanabe, T; Naito, M; et al. Regression of established tumors expressing P-glycoprotein by combinations of adriamycin, cyclosporin derivatives, and MRK-16 antibodies. JOURNAL OF THE NATIONAL CANCER INSTITUTE 89:512-518(1997).
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COA
Certificate of Analysis
