Anti-ADH1A (aa 298-375) polyclonal antibody

Species Reactivity

Human

Immunogen

ADH1A (NP_000658, 298 a.a. ~ 375 a.a) partial recombinant protein with GST tag. The sequence is DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKIN EGFDLLHSGKSIRTILMF

Conjugate

Alternative Names

ADH1A; alcohol dehydrogenase 1A (class I), alpha polypeptide; ADH1; alcohol dehydrogenase 1A; ADH, alpha subunit; aldehyde reductase; alcohol dehydrogenase subunit alpha; alcohol dehydrogenase 1 (class I), alpha polypeptide;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.

Pathway

Abacavir metabolism; Biological oxidations; Chemical carcinogenesis; Drug metabolism - cytochrome P450