Anti-ADH1A monoclonal antibody, clone FQS5551

Antibody Isotype

IgG

Clone

FQS5551

Species Reactivity

Human

Immunogen

Recombinant protein within human Alcohol Dehydrogenase aa 1-200.

Conjugate

Application Notes

WB: 1/1000 - 1/10000. Predicted molecular weight: 40 kDa; IP: 1/10 - 1/100; IHC-P: 1/100 - 1/250.

Alternative Names

ADH1; alcohol dehydrogenase 1 (class I); alcohol dehydrogenase 1; ADH-A2; class I alcohol dehydrogenase; alcohol dehydrogenase A subunit; alcohol dehydrogenase 1, complex; alcohol dehydrogenase 1 temporal, liver; alcohol dehydrogenase 1, electrophoretic;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.

Pathway

Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Ethanol oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem;