Specifications
Species Reactivity
Mouse; Rat; Hamster
Immunogen
His-tag fusion protein, corresponding to cytoplasmic, C terminal amino acids 1548-1582 of Rat SUR1.
Applications
Application Notes
WB: 1 μg/ml; IHC-P: 0.1 - 1 μg/ml; ICC/IF: 0.1 - 10 μg/ml;
Target
Alternative Names
ABCC8; ATP-binding cassette, subfamily C (CFTR/MRP), member 8; ATP-binding cassette sub-family C member 8; sulfonylurea receptor 1; sulphonylurea receptor 1; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, sub-family C (CFTR/
Product Background
Antigen Description
Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release.
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Type II diabetes mellitus, organism-specific biosystem; Type II diabetes mellitus, conserved biosystem;
Citations
Publication ()
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COA
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