Specifications
Immunogen
Bacterial fusion protein, containing amino acids 764-964 of Human MRP6.
Applications
Application Notes
IHC-Fr: 1/20 - 1/50.
Target
Alternative Names
ABCC8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; HRINS, SUR; ATP-binding cassette sub-family C member 8; ABC36; HHF1; HI; MRP8; PHHI; sulfonylurea receptor (hyperinsulinemia); SUR1; TNDM2; sulfonylurea receptor 1; ATP-binding cassette trans
Product Background
Antigen Description
May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS).
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; ATP sensitive Potassium channels, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Inwardly rectifying K+ channels, organism-specific biosystem;
Citations
Publication ()
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COA
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