Anti-ABCA1 monoclonal antibody (CABT-50918RM)

Rat Anti-Mouse ABCA1 monoclonal antibody for FC; IF

Specifications


Host Species
Rat
Antibody Isotype
IgG2a
Clone
5A1-1422
Species Reactivity
Mouse
Immunogen
ABCA1 transfected HeLa cells.
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 1/10 - 1/200;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ABCA1; ATP-binding cassette, sub-family A (ABC1), member 1; Abc1; ABC-1; ATP-binding cassette sub-family A member 1; ATP-binding cassette 1
Entrez Gene ID
UniProt ID
P41233

Product Background


Pathway
ABC transporters; Fat digestion and absorption; Fatty acid, triacylglycerol, and ketone body metabolism; HDL-mediated lipid transport; Lipid digestion, mobilization, and transport; Lipoprotein metabolism; Metabolism; Metabolism of lipids and lipoproteins;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Rosenblat, M; Vaya, J; et al. Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine. ATHEROSCLEROSIS 179:69-77(2005).
Tsou, CY; Chen, CY; et al. Activation of soluble guanylyl cyclase prevents foam cell formation and atherosclerosis. ACTA PHYSIOLOGICA 210:799-810(2014).

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