Anti-ABCA1 monoclonal antibody (DCABH-6149)

Mouse anti-Human ABCA1 monoclonal antibody for FC, IHC-P, WB

Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
IK2
Species Reactivity
Mouse, Rat, Human
Immunogen
Recombinant fragment corresponding to ABCA1.
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 2μg/106 cells; IHC-P: 0.2 μg/ml; WB: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ABCA1; ATP-binding cassette, sub-family A (ABC1), member 1; ABC1, HDLDT1; ATP-binding cassette sub-family A member 1; Tangier disease; TGD
Entrez Gene ID
UniProt ID

Product Background


Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket
Mouse IgG2b Isotype Control DAGIC1236 FC EIA WB Mouse PDF Inquiry

References


Nagao, K; Takahashi, K; et al. ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I binding. JOURNAL OF LIPID RESEARCH 53:126-136(2012).
Cignarella, A; Engel, T; et al. Pharmacological regulation of cholesterol efflux in human monocyte-derived macrophages in the absence of exogenous cholesterol acceptors. ATHEROSCLEROSIS 179:229-236(2005).

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