Anti-ABCA1 monoclonal antibody (DCABH-7340) Knockout Validated

Mouse anti-Human ABCA1 monoclonal antibody for IHC-P, ICC/IF, FC, WB, ELISA, IP

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
BC.I21
Species Reactivity
Mouse, Rat, Chicken, Cow, Human
Immunogen
Recombinant fragment, corresponding to amino acids 1800-2260 of Human ABCA1.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1/200; Flow Cyt: 1-2μg/106 cells; WB: 1/200 - 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ABCA1; ATP-binding cassette, sub-family A (ABC1), member 1; ABC1, HDLDT1; ATP-binding cassette sub-family A member 1; Tangier disease; TGD
Entrez Gene ID
UniProt ID

Product Background


Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Ikeda, Y; Abe-Dohmae, S; et al. Posttranscriptional regulation of human ABCA7 and its function for the apoA-I-dependent lipid release. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 311:313-318(2003).
Trogan, E; Feig, JE; et al. Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 103:3781-3786(2006).

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