Anti-AARSD1 polyclonal antibody (DPAB-DC3329)

Goat Anti-Human AARSD1 (internal region) polyclonal antibody for WB, ELISA

Specifications


Host Species
Goat
Species Reactivity
Human
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human AARSD1. The sequence is C-IEFYAKVNSKDSQDK
Conjugate
Unconjugated

Applications


Application Notes
ELISA: 1:32000; WB: 0.5 -2 μg/mL. & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
AARSD1; alanyl-tRNA synthetase domain containing 1; alanyl-tRNA editing protein Aarsd1; alanyl-tRNA synthetase domain-containing protein 1
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
AARSD1 (alanyl-tRNA synthetase domain containing 1) is a protein-coding gene. Diseases associated with AARSD1 include ovarian cancer. GO annotations related to this gene include alanine-tRNA ligase activity and molecular_function. An important paralog of this gene is PTGES3. The function about AARSD1 antigen include ATP binding; Ser-tRNA(Ala) hydrolase activity; alanine-tRNA ligase activity; metal ion binding.

Citations


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References


MILLER, WT; HILL, KAW; et al. EVIDENCE FOR A CYSTEINE-HISTIDINE BOX METAL-BINDING SITE IN AN ESCHERICHIA-COLI AMINOACYL-TRANSFER RNA-SYNTHETASE. BIOCHEMISTRY 30:6970-6976(1991).
Beebe, K; Mock, M; et al. Distinct domains of tRNA synthetase recognize the same base pair. NATURE 451:90-U14(2008).

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