Rabbit Anti-Human AARS (N-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to residues near the N terminal of human alanyl-tRNA synthetase

Conjugate

Application Notes

WB: 1:200-1:1000
IHC: 1:25-1:100

General Notes

This product (Catalog No. DPABH-03643) is a rabbit-derived IgG polyclonal antibody raised against human AARS. It has been affinity purified by protein A. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
DPABH-03643 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:25–1:100) applications.
DPABH-03643 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

CMT2N; AARS; alanyl-tRNA synthetase

Entrez Gene ID

UniProt ID