Anti-14-3-3 monoclonal antibody (DCABH-3890)

Mouse anti-Human 14-3-3 monoclonal antibody for WB, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4G8
Species Reactivity
Human
Immunogen
Recombinant full length protein (Human 14-3-3 gamma).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 - 2 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, alpha polypeptide , YWHAA; 14-3-3 protein beta/alpha; 14 3 3 alpha; 14 3 3 beta
Entrez Gene ID
UniProt ID

Product Background


Pathway
ARMS-mediated activation, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Axon guidance, organism-specific biosystem;

Citations


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References


Dong, XY; Zhu, F; et al. Transplanted bone marrow mesenchymal stem cells protects myocardium by regulating 14-3-3 protein in a rat model of diabetic cardiomyopathy. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:3714-3723(2014).
Gong, FH; Wang, GL; et al. 14-3-3 beta regulates the proliferation of glioma cells through the GSK3 beta/beta-catenin signaling pathway. ONCOLOGY REPORTS 30:2976-2982(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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