Human ADIPOR1 peptide

Specificity

Widely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the ADIPOR family.

Alternative Names

The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]

Function

hormone binding; identical protein binding; protein heterodimerization activity; protein kinase binding; receptor activity;

Synonyms

ADIPOR1; adiponectin receptor 1; CGI45; PAQR1; ACDCR1; CGI-45; TESBP1A; adiponectin receptor protein 1; progestin and adipoQ receptor family member I;