Anti-ATR monoclonal antibody (DMABT-H13107)

Mouse anti-Human ATR monoclonal antibody for IHC, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2F0
Species Reactivity
Human
Immunogen
ATR (NP_001175, 2545 a.a. ~ 2644 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
ATR; ataxia telangiectasia and Rad3 related; serine/threonine-protein kinase ATR; FRP1; MEC1; mitosis entry checkpoint 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of ATR in response to replication stress, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chromosome Maintenance, organism-specific biosystem;

Citations


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References


Stokes, MP; Silva, JC; et al. Quantitative Profiling of DNA Damage and Apoptotic Pathways in UV Damaged Cells Using PTMScan Direct. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 14:286-307(2013).
Rybaczek, D; Bodys, A; et al. H2AX foci in late S/G2- and M-phase cells after hydroxyurea- and aphidicolin-induced DNA replication stress in Vicia. HISTOCHEMISTRY AND CELL BIOLOGY 128:227-241(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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