YFV Envelope Viral Like Particles was packaged in HEK293T cells. It is the replication-incompetent particles in which the YFV Envelope (with 6His-tag at its C-terminal) was pseudo-typed as the lentiviral particles' surface envelope protein.
Target
YFV
Nature
Recombinant
Tag/Conjugate
His
Alternative Names
Yellow Fever Virus; YFV Envelope protein; YFV E protein
Format
Liquid
Concentration
1×108 VP/ml
Buffer
PBS buffer
Preservative
None
Storage
Store at -80°C. Avoid multiple freeze/thaw cycles.
Introduction
The YFV genome is an 11kb single-stranded positive-sense RNA genome coding for a polyprotein, which is post- and co-translationally processed into three structural proteins and seven non-structural proteins. The largest of the structural proteins, the envelope (E) protein (445aa), is the major component of the virion surface. It is the primary immunogen and plays a central role in receptor binding and membrane fusion. It is the primary immunogen and plays a central role in receptor binding and membrane fusion.
Keywords
Yellow Fever Virus; Envelope protein; YFV
Citations
Publication ()
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Q: I wanted to confirm if the Recombinant Yellow Fever Virus (YFV) Envelope VLP His (Cat# DAG-WT369) antigen is suitable for an activation assay, specifically for in-vitro stimulation for flow cytometry and ELISPOT assays.
A: The YFV Envelope (Cat# DAG-WT369) has been assembled as the lentiviral particles' surface antigens. This means it can be used as a ready-to-use YFV Envelope antigen, for raising specific antibodies, for validating anti-YFV Envelope antibodies, in vaccine development, and for other validation assays.
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