General Description
Vitamin B1, also referred to as thiamine, is an important water-soluble vitamin, an essential micronutrient for humans and animals. It is an essential micronutrient that plays a critical role in the maintenance of normal neural activity and enhances cardiovascular function. Vitamin B1 deficiency has a negative impact on health and leads to severe diseases such as beriberi and Wernicke-Korsakoff syndrome. In the body, thiamine can form derivatives; the most well-characterized of which is thiamine pyrophosphate (TPP), a coenzyme in the catabolism of sugars and amino acids. The dietary reference intake for vitamin B1 is 0.9–1.2 mg/day in adults and for children, the recommended daily intake (RDA) is 0.4–0.6 mg/day and 0.2–0.3 mg/day for infants. (Thiamin Fact Sheets for Health Professionals. 2016; Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. 1998)