serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids
Tacrolimus ELISA Kit can be used in quantitative and qualitative analysis of tacrolimus in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Open kit immediately upon receipt. Store components at -20°C (NOTE: exceptions below) for 6 months or until expiration date. Avoid any freeze/thaw cycles
0.156 - 10 ng/mL
< 0.069 ng/mL
Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is an immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system and so lower the risk of organ rejection. It is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, and the skin condition vitiligo. It is a 23-membered macrolide lactone discovered in 1984 from fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. It reduces interleukin-2 (IL-2) production by T-cells.