Kanamycin

Kanamycin Full Name

Kanamycin

Kanamycin Introduction

Kanamycin is a broad-spectrum antibiotic widely used in veterinary medicine and as a second-line antibiotic to treat serious infections. Kanamycin interferes with the prokaryotic 30S ribosomal unit, which results in prokaryotic mistranslation and inhibition of protein translocation during protein synthesis. The residual antibiotics in animal-derived food are proven to be harmful to human health and therefore should be strictly controlled in the food industry. Kanamycin is widely used in clinical practice due to its good antimicrobial properties. However, excessive use of kanamycin in food and medicine may cause serious side effects, such as nephrotoxicity, ototoxicity, neuromuscular blocking effects, hematopoietic system toxicity, and allergic reactions.

It is extensively utilized as a treatment for bacterial infections in both medicine and agriculture. Kanamycin is frequently administered to feed as a veterinary medicine in animal husbandry. Unfortunately, the low price of the drug has led to its misuse, augmenting bacterial resistance and making treating late-stage infections more difficult. Additionally, excessive ingestion of meat products containing Kanamycin residues by humans can result in ototoxicity, nephrotoxicity, and respiratory failure. Kanamycin is an effective antibiotic for the treatment of certain infections, but its usage should be carefully monitored due to the potential for serious side effects. Additionally, the development of sensitive detection methods is crucial for ensuring food safety and effective point of care testing.

Alternate Names for Kanamycin

Kanamycin

• 1. T.T. Liu et al. Sensitive lateral flow immunoassay strips based on Fe3+-chelated polydopamine nanospheres for the detection of kanamycin. Food Chem, 2023