General Description
Salinomycin is a polyether monocarboxylic acid produced by Streptomyces albus, classically used as an agricultural antibiotic to prevent coccidiosis in chickens. It exhibits high antimicrobial activity against Gram-positive bacteria, Clostridium perfringens, mycobacteria, and some filamentous fungi. Because of its low drug resistance and in food, Salinomycin has broad market expectation. However, they are highly toxic and may cause headaches, nausea, nosebleeds, ocular opacity, and myocardial damage in humans. The maximum residue limits for salinomycin in chicken tissues in Japan (2006) and Canada (2015) are 500 and 200 μg/kg, respectively. The USA(2016) and the European Union(2010) have not issued related provisions. (Tefas L. R., et al., 2021; Tian W., et al., 2017)