A DNA sequence encoding the human osteopontin protein (a.a.17-166) was expressed with His-tag at the N-terminus
Target
SPP1
Nature
Recombinant
Tag/Conjugate
His
Molecular Weight
21 kDa
Alternative Names
Osteopontin; OPN; Bone sialoprotein I; BSP-1; BNSP; T lymphocyte activating factor; ETA-1; Secreted phosphoprotein 1; SPP1; Anti-Rick Secondary body; Ric
Purity
> 95% as determined by SDS-PAGE
Format
Lyophilized
Buffer
Lyophilized from sterile PBS, pH 7.4
Preservative
None
Storage
Store at -20°C to -80°C
Introduction
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Keywords
Osteopontin; SPP1; ETA-1; OPN
Citations
Publication ()
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