Product Overview
A DNA sequence encoding the human SorLA (a.a. 82-2135) was expressed with His tag at the C-terminus
Purity
> 95% as determined by SDS-PAGE
Concentration
Batch dependent - please inquire should you have specific requirements
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with trehalose
Storage
Store at -20°C to -80°C
Reconstitution
Reconstitute at 1.00 mg/mL in PBS
Introduction
Sortilin-related receptor, L(DLR class) A repeats containing is a protein that in humans is encoded by the SORL1 gene. SORL1 (also known as SORLA, SORLA1, or LR11) is a neuronal apolipoprotein E receptor, the gene for which is predominantly expressed in the central nervous system.
Keywords
Sortilin-related receptor preproprotein; SorLA; SORL1 protein
Citations
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Jacobsen, L; Madsen, P; et al. Molecular characterization of a novel human hybrid-type receptor that binds the alpha(2)-macroglobulin receptor-associated protein. JOURNAL OF BIOLOGICAL CHEMISTRY 271:31379-31383(1996).
Tsukamoto, S; Takeuchi, M; et al. Tetraspanin CD9 modulates ADAM17-mediated shedding of LR11 in leukocytes. EXPERIMENTAL AND MOLECULAR MEDICINE 46:-(2014).
COA
Certificate of Analysis
