Molecular Weight
15.7 kDa
Purity
> 95% as determined by SDS-PAGE
Buffer
Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile, 0.1% TFA
Introduction
The protein encoded by this gene is a member of the TGF-β superfamily. Like other members of the bone morphogenetic protein family of proteins, it plays a key role in the transformation of mesenchymal cells into bone and cartilage. It is inhibited by noggin and a similar protein, chordin, which are expressed in the Spemann-Mangold Organizer. BMP7 may be involved in bone homeostasis. It is expressed in the brain, kidneys and bladder
Keywords
Bone morphogenetic protein 7; BMP-7; BMP7
Citations
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Kusumegi, T; Tanaka, J; et al. BMP7/ActRIIB regulates estrogen-dependent apoptosis: New biomarkers for environmental estrogens. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 18:1-11(2004).
Bais, MV; Wigner, N; et al. BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells. BONE 45:254-266(2009).
COA
Certificate of Analysis
