Recombinant HIV-1 p24 Fragment (M:C_05NOVAX25)

Objective To assess the prevalence and risk factors of drug-resistant tuberculosis (TB), the fifth national anti-TB drug resistance survey was conducted in Thailand. Methods A cross-sectional study was conducted by stratified cluster sampling with probability proportional to size of TB cases from public health facilities in 100 clusters throughout Thailand from August 2017 to August 2018. Susceptibility testing of TB isolates to first- and second-line anti-TB drugs was performed on Lowenstein-Jensen medium using the indirect proportion method. Multiple imputation was done for handling missing data using Stata 16. The proportion of TB cases with drug resistance was determined. The odds ratio was used to evaluate risk factors associated with drug-resistant TB. Results Among 1501 new TB and 69 previously treated TB cases, 14.0% [95% confidence interval (CI): 12.1-16.1] and 33.4% (95% CI: 23.6-44.8), respectively, had resistance to any anti-TB drug. Multidrug-resistant TB accounted for 0.8% (95% CI: 0.5-1.4) of new TB cases and 13.0% (95% CI: 6.5-24.4) of previously treated TB cases. Drug-resistant TB was associated with prior TB treatment [odds ratio (OR), 2.9; 95% CI: 1.6-5.0], age at 45-54 years (OR, 1.6; 95% CI: 1.0-2.4), male (OR, 1.5; 95% CI: 1.0-2.1) and human immunodeficiency virus (HIV) infection (OR, 1.6; 95% CI: 1.0-2.4). Conclusions The burden of drug-resistant TB remains high in Thailand. Intensified prevention and control measures should be implemented to reduce the risks of drug-resistant TB in high-risk groups previously treated, especially individuals of late middle age, males and those with coinfection of TB and HIV.

Bridewealth is recognized as vital in the reproduction and reconfiguration of Pacific environments and women play an integral role in this process. In contemporary Papua New Guinea (PNG), bridewealth is reconfigured by kin to acknowledge the considered actions of women as they enter into relationships with men. This paper will explore how women's choices impact and influence their experience of these exchanges and determine the role of women and their kin as they undertake these practices. Here I aim to understand how the social relatedness that frames bridewealth exchanges enables the practices of bridewealth to be used as a tool for recognition of women's choices, autonomy and personhood. Although women enter into relationships without initial kin approval, bridewealth practices converge ultimately with a women's autonomous choice of husband. Wardlow suggests (2006:86) 'bridewealth confers value and dignity on female gender', and going beyond her observation, I show that bridewealth has been useful in achieving this in regard to managing and supporting social, kin and affinal relationships. This article will explore two cases, to identify what each tells us about women's ability to act in ways that are beneficial to them and important to kin. I show how moral evaluations frame (pasin) and recognize (luksave) kin and social relationships that ultimately constitute their personhood.