Pyridoxamine [HSA]

Target

Pyridoxamine

Nature

Synthetic

Tag/Conjugate

HSA

Molecular Weight

app. 65 kDa

Alternative Names

pyridoxamine; 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL; Pyridoxylamine; 3-Pyridinemethanol, 4-(aminomethyl)-5-hydroxy-6-methyl-

Dilution

Test dependent

Purity

chromatography, dialysis

Format

Liquid

Concentration

1 mg/mL, conjugation ratio is app. 1:10 - 1:40.

Buffer

PBS

Preservative

0.05% sodium azide

Storage

Store at 4°C.

Introduction

Pyridoxamine is a monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a mouse metabolite, an iron chelator and a nephroprotective agent. It is a hydroxymethylpyridine, a monohydroxypyridine, an aminoalkylpyridine and a vitamin B6. It is a conjugate base of a pyridoxaminium(1+).

Antigen Description

Pyridoxamine, covalently linked to human serum albumin

Keywords

drug-HSA conjugate, drug-conjugate, pyridoxamin HSA conjugate