Native T. maccoyii Insulin Like Growth Factor II

Product Overview

Tuna Insulin Like Growth Factor II

Nature

Native

Tag/Conjugate

Unconjugated

Purity

> 95% (by HPLC and N-terminal sequence analysis)

Format

Lyophilized white powder. Dried from 0.1 M acetic acid and stored under nitrogen at a slight vacuum.

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Keywords

IGF2; insulin-like growth factor 2 (somatomedin A); C11orf43, chromosome 11 open reading frame 43; insulin-like growth factor II; FLJ44734; somatomedin-A; insulin-like growth factor type 2; IGF-II; PP9974; C11orf43; FLJ22066; dusigitumab; 1204390-13-5