Anti-RBBP4 Monoclonal antibody, clone 5B6

Antibody Isotype

IgG2a

Clone

5B6

Species Reactivity

Human

Immunogen

RBBP4 (NP_005601, 316 a.a.~426 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Application Notes

WB: 1:500-1000

Alternative Names

RBBP4; retinoblastoma binding protein 4; histone-binding protein RBBP4; NURF55; RbAp48; RBBP-4; CAF-I p48; CAF-1 subunit C; CAF-I 48 kDa subunit; MSI1 protein homolog; retinoblastoma-binding protein 4; retinoblastoma-binding protein p48; chromatin assembl

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing.

Pathway

Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; G0 and Early G1, organism-specific biosystem; Hedgehog signaling events mediated by Gli proteins, organism-specific biosystem;