Mouse Anti-Human IL15 Hybridoma [iJM-26-N221]

Name: Mouse Anti-Human IL15 Hybridoma [iJM-26-N221]
SKU: CSC-H0739
Rating: 5 (1 reviews)

Regulatory status: For research use only, not for use in diagnostic procedures.

COA

SDS

Datasheet

Summary

GeneralInformation

Immunogen

Yeast-derived human interleukin-15 (IL-15)

Fusion Species

Mouse X Mouse Hybridoma

Immunological Donor

Mouse spleen

Myeloma

AGX653

Clone

iJM-26-N221

Cell Line Description

Animals were immunized with yeast-derived human interleukin-15 (IL-15). Spleen cells were fused with AGX653 mouse myeloma cells. The antibody reacts with IL-15, an epithelium derived T cell growth factor.

Morphology

Lymphoblast

Growth Properties

Suspension

CultureMethod

Subculturing

Incubate cells at 37°C with 5% CO2 in air atmosphere, renew medium every 2-3 days, start cells at 1x10^5 cells/mL and maintain cultures between 1x10^5-1x10^6 cells/ml

Storage

Liquid nitrogen vapor phase.

Target

Synonyms

IL15; interleukin 15; interleukin-15; IL 15; MGC9721; IL-15;

Entrez Gene ID

3600

UniProt ID

P40933

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

Transgenic expression of IL15 selectively expands antigen specific cytotoxic T cells (CTLs) enhancing their anti-tumor effect in vivo.

BLOOD

Authors: Vera, J.; Quintarelli, C.; Savoldo, B.; Giordano, G.; Foster, A.; Pule, M.; Heslop, Helen; Rooney, C.; Brenner, Malcolm; Dotti, G.

Abstract

IL15 Enhances Proliferation and Effector Function of Antigen-Specific Cytotoxic T Lymphocytes (CTLs) and Mitigates the Suppressive Action of Regulatory T Cells (Tregs).

BLOOD

Authors: Perna, Serena Kimi; De Angelis, Biagio; Pagliara, Daria; Zhan, Lan; Rooney, Cliona M.; Heslop, Helen E.; Brenner, Malcolm K.; Dotti, Gianpietro; Savoldo, Barbara

Abstract