Anti-Chlamydia Polyclonal antibody

BackgroundWhile HIV Testing Services (HTS) have increased, many South Africans have not been tested. Non-communicable diseases (NCDs) are the top cause of death worldwide. Integrated NCD-HTS could be a strategy to control both epidemics. Healthcare service strategies depends partially on positive user experience. We investigated client satisfaction of services and clinic flow time of an integrated NCD-HTS clinic.MethodsThis prospective, cross-sectional study evaluated HTS client satisfaction with an HTS clinic at two phases. Phase 1 (February-June 2018) utilised standard HTS services: counsellor-led height/weight/blood pressure measurements, HIV rapid testing, and symptoms screening for sexually transmitted infections/Tuberculosis. Phase 2 (June 2018-March 2019) further integrated counsellor-led obesity screening (body mass index/abdominal circumference measurements), rapid cholesterol/glucose testing; and nurse-led Chlamydia and human papilloma virus (HPV)/cervical cancer screening. Socio-demographics, proportion of repeat clients, clinic flow time, and client survey data (open/closed-ended questions using five-point Likert scale) are reported. Fisher's exact test, chi-square analysis, and Kruskal Wallis test conducted comparisons. Multiple linear regression determined predictors associated with clinic time. Content thematic analysis was conducted for free response data.ResultsTwo hundred eighty-four and three hundred thirty-three participants were from Phase 1 and 2, respectively (N =617). Phase 1 participants were significantly older (median age 36.5 (28.0-43.0) years vs. 31.0 (25.0-40.0) years; p =0.0003), divorced/widowed (6.7%, [n =19/282] vs. 2.4%, [n =8/332]; p =0.0091); had tertiary education (27.9%, [n =79/283] vs. 20.1%, [n =67/333]; p =0.0234); and less female (53.9%, [n =153/284] vs 67.6%, [n =225/333]; p =0.0005), compared to Phase 2. Phase 2 had 10.2% repeat clients (n =34/333), and 97.9% (n =320/327) were 'very satisfied' with integrated NCD-HTS, despite standard HTS having significantly shorter median time for counsellor-led HTS (36.5, interquartile range [IQR]: 31.0-45.0 vs. 41.5, IQR: 35.0-51.0; p <0.0001). Phase 2 associations with longer clinic time were clients living together/married (est=6.548; p =0.0467), more tests conducted (est=3.922; p <0.0001), higher overall satisfaction score (est=1.210; p =0.0201). Those who matriculated experienced less clinic time (est=-7.250; p =0.0253).ConclusionsIt is possible to integrate counsellor-led NCD rapid testing into standard HTS within historical HTS timeframes, yielding client satisfaction. Rapid cholesterol/glucose testing should be integrated into standard HTS. Research is required on the impact of cervical cancer/HPV screenings to HTS clinic flow to determine if it could be scaled up within the public sector.

The Sexual and Reproductive Health Burden Index (SRHBI) was developed to provide a composite spatial measure of sexual and reproductive health (SRH) indicators that can be widely adopted by urban public health departments for the planning of SRH services. The index was constructed using eight indicators: teen births, low birthweight, infant mortality, new HIV diagnoses, people living with HIV, and incidences of gonorrhea, chlamydia, and syphilis. Chicago Department of Public Health data (2014-2017) were used to calculate index scores for Chicago community areas; scores were mapped to provide geovisualization and global Moran'sIwas calculated to assess spatial autocorrelation. Cronbach's alpha was calculated to assess internal reliability of the SRHBI. Pearson correlations were conducted to assess concurrent validity and correlation with community-level factors. Linear regression was conducted to assess community-level predictors of the SRHBI. Application of the SRHBI in Chicago demonstrates substantial variation in SRH burden across Chicago's urban landscape with significant spatial autocorrelation of scores (I = .580,p = .001). Internal reliability of the measure was excellent with alpha = .937. The SRHBI was significantly correlated with other indicators of SRH including rate of prenatal care initiation in the first trimester, rate of preterm births, reported sexual assault incidence, cervical cancer incidence, prostate cancer incidence, and rate of smoking during pregnancy. This suggests good concurrent validity of the measure. Linear regression revealed that the percent of Black residents, percent of household couples that are same-sex, community violence, economic hardship, and population density were significant predictors of the SRHBI. The SRHBI provides a valid, useful, and replicable measure to assess and communicate community-level SRH burden in urban environments. The SRHBI may be scaled through a multi-city public data dashboard and utilized by urban public health departments to optimally target and tailor SRH interventions to communities.