Magic™ Rabbit Anti-Mouse IL-1RA Monoclonal antibody, clone 351319H4

Antibody Isotype

IgG

Clone

351319H4

Species Reactivity

Mouse

Immunogen

Fusion Protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT945 - DMAB-CPT946
Cytometric Bead Array: 0.625-80 ng/mL

General Notes

This product (Catalog No. DMAB-CPT945) is a rabbit-derived monoclonal antibody raised against mouse Mouse IL1RN. It has been affinity purified by Protein A. Interleukin-1 receptor antagonist (IL-1RA) is a critical member of the IL-1 family of cytokines, which plays a significant role in modulating inflammatory responses. IL-1RA exists in two main forms: a secreted form (sIL-1Ra) and an intracellular form (icIL-1Ra). The secreted form is produced by various cells including monocytes, macrophages, neutrophils, and other cells, while the intracellular form is found in keratinocytes and other epithelial cells, as well as in monocytes and fibroblasts. IL-1RA is important in host defense against endotoxin-induced injury and is produced in numerous experimental animal models of disease, as well as in human autoimmune and chronic inflammatory diseases. It acts as an anti-inflammatory agent by maintaining the balance between pro-inflammatory IL-1α/β and its own anti-inflammatory effects.
DMAB-CPT945 is suitable for use in Cytometric Bead Array (0.625-80 ng/mL) application.
DMAB-CPT945 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Il1rn; IL-1RA; IL 1ra; 240208G3; interleukin 1 receptor antagonist

Entrez Gene ID

UniProt ID