The anti-H2Kd/H-2Dd monoclonal antibody (clone 34-1-2S) is a mouse-derived antibody that targets MHC class I alloantigens, specifically H-2Kd and H-2Dd. These antigens are expressed on the surface of nucleated cells in mice with the H-2Kd/H-2Dd haplotype. The antibody is critical for antigen presentation to T cells expressing CD3/TCR and CD8 proteins. This antibody is known for its cross-reactivity with other MHC class I alloantigens, including those of the H-2Kb, H-2Ks, H-2Kr, H-2Kq, and H-2Kp haplotypes. It is commonly used in flow cytometry for the analysis of mouse splenocytes and other cell types. This antibody is a valuable tool for researchers studying immune responses by helping to identify and characterize cells based on their MHC class I expression.
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Alternative Names
A 28; A 9; Antigen presenting molecule; Aw 24; Aw 68; CLASS I HISTOCOMPATIBILITY ANTIGEN; H2 K1; H2K; HLA A; HLA class I histocompatibility antigen A 1 alpha chain
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