Full length human sequence FTCD enzyme (isoform A) with hexa-Histidine tag
Target
LC1
Nature
Recombinant
Tag/Conjugate
His
Molecular Weight
60 kDa
Alternative Names
Liver cytosol antigen 1; lc1; FTCD
Purity
> 90% , as determined by SDS-PAGE
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements
Buffer
20% Glycerol
Preservative
50 mM Imidazole
Storage
Store at -20°C
Introduction
LC1 is a marker for autoimmune hepatitis (AIH) type II and antibodies against LC-1 are found to be detected in up to 50% of cases. Immunofluorescence of LC-1 is often not identified due to the brightness of LKM-1 obscuring accurate visualisation. Some occurrences of anti-LC-1 in conjunction with antinuclear antibodies (ANA) and smooth muscle antibodies (SMA) in patients with chronic hepatitis C and autoimmune hepatitis, is known. Some case studies have shown that anti-LC-1 is found as the only serological marker in patients with AIH type II.
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