Kynurenic Acid ELISA kit

Sample

Serum, plasma and other biological fluids

Species Reactivity

None

Intended Use

For the quantitative measurement of KYNA in serum, plasma and other biological fluids.

Storage

Open kit immediately upon receipt. Store components at -20°C (NOTE: exceptions below) for 6 months or until expiration date. Avoid any freeze/thaw cycles.

Precision

Intra-assay reproducibility was evaluated with 20 replicates of 3 samples representing low, middle and high level target. Inter-assay reproducibility was evaluated with 3 samples representing low, middle and high level target using 8 replicates on each of 3 plates.

Detection Range

24.69 - 2,000 ng/mL

Detection Limit

< 9.13 ng/mL (Derived by linear regression of OD450 of the Mean Blank + 2xSD)

General Description

Kynurenic acid (KYNA) is a downstream metabolite produced along the Kynurenine Pathway well-known to possess several neuromodulatory functions, as well as immuno-modulatory properties. Measurement of KYNA in biological samples has been presented as a possible biomarker in several diseases including neurological or psychiatric disorders.