Product Overview
A DNA sequence encoding Influenza B (B/Brisbane/60/2008) Neuraminidase (4CPL_A) (Met1-Leu466), termed as NA, was expressed.
Molecular Weight
The recombinant influenza B (B/Brisbane/60/2008) Neuraminidase consists of 466 amino acids and predicts a molecular mass of 51.1 kDa.
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Alternative Names
Influenzavirus B; Influenza B virus; IBV; IBV Neuraminidase; IBV NA
Buffer
Lyophilized from sterile PBS, 1%Triton X-100 PH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Storage
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Introduction
Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell. Influenza neuraminidase is composed of four identical subunits arranged in a square. It is normally attached to the virus surface through a long protein stalk. The active sites are in a deep depression on the upper surface. They bind to polysaccharide chains and clip off the sugars at the end. The surface of neuraminidase is decorated with several polysaccharide chains that are similar to the polysaccharide chains that decorate our cell surface proteins. Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of the influenza virus.
Keywords
Influenzavirus B; Influenza B virus; IBV; IBV Neuraminidase; IBV NA
Citations
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