Product Overview
It contains AA Asp 19 - Arg 338 (Accession # AAO46082.1).
Molecular Weight
This protein carries an Avi tag at the C-terminus, followed by a polyhistidine tag.
The protein has a calculated MW of 38.8 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Alternative Names
HA; Hemagglutinin; Hemagglutinin HA; IAV; Influenza A; IAV HA; Influenza A HA; IAV HA1; Influenza A HA1
Purity
>95% as determined by SDS-PAGE
Format
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Concentration
Batch dependent - please inquire should you have specific requirements.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss is observed after storage at:
4-8°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Antigen Description
Influenza, commonly known as "the flu", is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease. The serotypes that have been confirmed in humans, ordered by the number of known human pandemic deaths, are: H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, H10N7, H7N9. H7N9 is a serotype of the species Influenzavirus A (avian influenza virus or bird flu virus). H7 normally circulates amongst avian populations with some variants known to occasionally infect humans. An H7N9 virus was first reported to have infected humans in 2013 in China.
Keywords
HA; Hemagglutinin; Hemagglutinin HA; IAV; Influenza A; IAV HA; Influenza A HA; IAV HA1; Influenza A HA1
Citations
Publication ()
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COA
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