Application: We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT1169 - DMAB-CPT1170
Summary
Specifications
Antibody Isotype
IgG
Clone
351400F8
Species Reactivity
Human
Immunogen
SMPD1,ASM fusion protein
Conjugate
Unconjugated
Applications
Application Notes
We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT1169 - DMAB-CPT1170 Cytometric Bead Array: 0.78-100 ng/mL
General Notes
This product (Catalog No. DMAB-CPT1169) is a rabbit-derived monoclonal antibody raised against human SMPD1. It has been affinity purified by Protein A. SMPD1(Sphingomyelin phosphodiesterase) is also named as ASM and belongs to the acid sphingomyelinase family. It is an important enzyme in sphingolipid metabolism and plays key roles in apoptosis, immunity, development, and cancer. The deficient activity of this enzyme results in Types A and B Niemann-Pick disease (NPD). This protein has 4 isoforms produced by alternative splicing. SMPD1 can produce a 60 kDa peptide with its signal peptide missing. DMAB-CPT1169 is suitable for use in Cytometric Bead Array (0.78-100 ng/mL) application. DMAB-CPT1169 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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