One unit is defined as the amount of enzyme which hydrolyzes 1 μmole of sphingomyelin per minute at 37°C under the conditions specified in the assay procedure.
Target
Sphingomyelinase
Molecular Weight
37.5 kDa
Application Notes
This enzyme is useful for enzymatic determination of sphingomyelin
Format
Lyophilized
Buffer
Enzyme dilution buffer
Storage
Store at -20°C
Introduction
Sphingomyelin phosphodiesterase is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into phosphocholine and ceramide. The activation of SMase has been suggested as a major route for the production of ceramide in response to cellular stresses.
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