Magic™ Rabbit Anti-Human ROCK1 Monoclonal antibody, clone 341534F5

Antibody Isotype

IgG

Clone

341534F5

Species Reactivity

Human

Immunogen

ROCK1 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT739 - DMAB-CPT740
Sandwich ELISA: 15.6-1000 pg/mL

General Notes

This product (Catalog No. DMAB-CPT740) is a rabbit-derived monoclonal antibody raised against human ROCK1. It has been affinity purified by Protein A. ROCK1, also named as p160ROCK and NY-REN-35, belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. ROCK1 phosphorylates and activates DAPK3, which then regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. ROCK1 is required for centromere positioning and centromere-dependent exit from mitosis.
DMAB-CPT740 is suitable for use in Sandwich ELISA (15.6-1000 pg/mL) application.
DMAB-CPT740 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Renal carcinoma antigen NY-REN-35; P160ROCK; p160 ROCK-1; p160 ROCK 1; EC:2.7.11.1; Rho-associated, coiled-coil containing protein kinase 1; ROCK1

Entrez Gene ID

UniProt ID