Magic™ Rabbit Anti-Human RNF31 Monoclonal antibody, clone 341557C4

Antibody Isotype

IgG

Clone

341557C4

Species Reactivity

Human

Immunogen

RNF31 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT835 - DMAB-CPT836
Cytometric Bead Array: 1.25-20 ng/mL

General Notes

This product (Catalog No. DMAB-CPT836) is a rabbit-derived monoclonal antibody raised against human RNF31. It has been affinity purified by Protein A. RNF31 (Ring Finger Protein 31), also known as HOIP, is a crucial E3 ubiquitin ligase that forms the catalytic core of the Linear Ubiquitin Chain Assembly Complex (LUBAC). It regulates immune signaling, specifically NF-κB activation, by mediating Met1-linked linear polyubiquitination. RNF31 is highly expressed in various cancers and inflammatory diseases, making it a target for inhibiting tumor growth and promoting, say, T cell-mediated killing.
DMAB-CPT836 is suitable for use in Cytometric Bead Array (1.25-20 ng/mL) application.
DMAB-CPT836 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

FLJ10111; FLJ23501; HOIL 1 interacting protein; HOIP; ring finger protein 31; RNF31; ZIBRA

Entrez Gene ID

UniProt ID