Product Overview
Recombinant Human Nuclear pore complex protein Nup98-Nup96(NUP98) ,partial, C-terminal hFc-tagged.
Alternative Names
NUP98; nucleoporin 98kDa; nucleoporin 98kD; nuclear pore complex protein Nup98-Nup96; NUP96; Nup98-Nup96; GLFG-repeat containing nucleoporin; ADIR2; NUP196
Purity
Greater than 90% as determined by SDS-PAGE.
Buffer
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Storage
Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Introduction
Encoded by human NUP98 Gene (GLFG Nucleoporin Family), 937-amino acid Nucleoporin 98 kD (NUP98) is up regulated by interferon and generated through proteolytic cleavage of a 186 kD precursor yielding NUP98 and NUP96, both associated with the nuclear pore complex (NPC). NPC targeting of NUP96 and NUP98 is cleavage dependent, which may regulate assembly of the NPC, comprised of nearly fifty nucleoporins involved in signal-mediated nuclear import and export of protein and RNA.
Keywords
NUP98; nucleoporin 98kDa; nucleoporin 98kD; nuclear pore complex protein Nup98-Nup96; NUP96; Nup98-Nup96; GLFG-repeat containing nucleoporin; ADIR2; NUP196
Citations
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