General Notes
This product (Catalog No. DPABH-15986) is a rabbit-derived polyclonal antibody raised against human NUP98, targeting the amino acid region 629–894 of the protein. This antibody exhibits cross-reactivity with Human NUP98 from mouse and rat. It has been affinity purified by Protein A. NUP98 is a human gene that encodes a 98-kDa nucleoporin protein, a key structural component of the nuclear pore complex (NPC) that facilitates bidirectional transport of macromolecules between the nucleus and cytoplasm. This protein, also known as Nucleoporin 98, features phenylalanine-glycine (FG) repeat domains that interact with transport receptors, enabling selective nuclear import and export processes critical for cellular function. Beyond transport, NUP98 plays roles in gene expression regulation, mitotic checkpoint control, and nuclear pore assembly, with its dynamic localization allowing it to influence transcription in both nucleoplasmic and chromatin-bound contexts.
DPABH-15986 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-15986 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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