Magic™ Rabbit Anti-Human NOD2 Monoclonal antibody, clone 341438E21

Antibody Isotype

IgG

Clone

341438E21

Species Reactivity

Human

Immunogen

NOD2 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT891 - DMAB-CPT892
Cytometric Bead Array: 1.25-40 ng/mL

General Notes

This product (Catalog No. DMAB-CPT891) is a rabbit-derived monoclonal antibody raised against human NOD2. It has been affinity purified by Protein A. NOD2, also named as CARD15 and IBD1, induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. It confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Defects in NOD2 are the cause of Blau syndrome (BS). Defects in NOD2 are a cause of susceptibility to Crohn disease (CD). Defects in NOD2 are a cause of susceptibility to ulcerative colitis. Defects in NOD2 are the cause of early-onset sarcoidosis (EOS).
DMAB-CPT891 is suitable for use in Cytometric Bead Array (1.25-40 ng/mL) application.
DMAB-CPT891 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2; NOD2B; PSORAS1; nucleotide-binding oligomerization domain containing 2

Entrez Gene ID