Human Neisseria Gonorrhoeae Antibody ELISA Kit (DEIASL305)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Size
96T
Sample
Serum, plasma, tissue homogenates, other biological fluids
Species Reactivity
Human
Intended Use
This kit is designed for the quantitative in vitro determination of Human Neisseria gonorrhoeae antibody concentrations in human serum, plasma, tissue homogenates or other biological fluids.
Storage
The kit should be stored between 2°C and 8°C. The kit containing the reagents with designated shelf life should be stored between 2°C and 8°C and should be returned to the refrigerator as soon as possible after use.
Precision
Intra-assay CV(%) and Inter-assay CV(%)are less than 15%.
Detection Range
1.25 ng/ml – 40 ng/ml.
Sensitivity
The minimum detection concentration is less than 0.1 ng/ml.
General Description
Gonorrhea (colloquially known as the clap) is a common human sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. The usual symptoms in men are burning with urination and penile discharge. Women, on the other hand, are asymptomatic half the time or have vaginal discharge and pelvic pain. In both men and women if gonorrhea is left untreated, it may spread locally causing epididymitis or pelvic inflammatory disease or throughout the body, affecting joints and heart valves. Treatment is commonly with ceftriaxone as antibiotic resistance has developed to many previously used medications. This is typically given in combination with either azithromycin or doxycycline. There have been some strains of gonorrhea showing resistance to ceftriaxone.

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References


MOYES, A; YOUNG, H; et al. EPIDEMIOLOGIC TYPING OF NEISSERIA-GONORRHOEAE - A COMPARATIVE-ANALYSIS OF 3 MONOCLONAL-ANTIBODY SEROTYPING PANELS. EUROPEAN JOURNAL OF EPIDEMIOLOGY 7:311-319(1991).
McQuillen, DP; Gulati, S; et al. Complement processing and immunoglobulin binding to Neisseria gonorrhoeae determined in vitro simulates in vivo effects. JOURNAL OF INFECTIOUS DISEASES 179:124-135(1999).

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