Magic™ Rabbit Anti-Human FZD5 Monoclonal antibody, clone 341553C23

Antibody Isotype

IgG

Clone

341553C23

Species Reactivity

Human

Immunogen

Frizzled 5 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT803 - DMAB-CPT804
Cytometric Bead Array: 1.25-20 ng/mL

General Notes

This product (Catalog No. DMAB-CPT804) is a rabbit-derived monoclonal antibody raised against human FZD5. It has been affinity purified by Protein A. Fzd5, is the receptor for the Wnt5A ligand. Fzd5 modulates cell fate and cell behavior during vertebrate development. It regulates hematopoiesis by the antagonism of the canonical Wnt pathway, resulting in a pool of quiescent hematopoietic stem cells, and regulates hematopoietic stem cell function in a paracrine fashion through several distinct mechanisms including modulating canonical Wnt signaling. It acts through noncanonical Wnt signaling to promote angiogenesis. It is also involved in control cell orientation, polarity, and directional movement in response to positional cues from chemokine gradients.
DMAB-CPT804 is suitable for use in Cytometric Bead Array (1.25-20 ng/mL) application.
DMAB-CPT804 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

FZD5; Fz-5; Fz 5; Frizzled-5; C2orf31

Entrez Gene ID

UniProt ID