Magic™ Rabbit Anti-Human FOXC2 Monoclonal antibody, clone 351514D7

Antibody Isotype

IgG

Clone

351514D7

Species Reactivity

Human

Immunogen

FOXC2 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT1153 - DMAB-CPT1154
Cytometric Bead Array: 0.313-40 ng/mL

General Notes

This product (Catalog No. DMAB-CPT1153) is a rabbit-derived monoclonal antibody raised against human FOXC2. It has been affinity purified by Protein A. Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene. FOXC2 is a member of the fork head box (FOX) family of transcription factors. FOX transcription factors are expressed during development and are associated with a number of cellular and developmental differentiation processes. FOXC2 is required during early development of the kidneys, including differentiation of podocytes and maturation of the glomerular basement membrane. It is also involved in the early development of the heart. FOXC2 is also involved in cancer metastases. In particular, expression of FOXC2 is induced when epithelial cells undergo an epithelial-mesenchymal transition (EMT) and become mesenchymal looking cells.
DMAB-CPT1153 is suitable for use in Cytometric Bead Array (0.313-40 ng/mL) application.
DMAB-CPT1153 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

MFH 1; Mesenchyme fork head protein 1; Forkhead-related protein FKHL14; Forkhead box protein C2; FKHL14; FOXC2

Entrez Gene ID

UniProt ID