Recombinant Human cTnC [His]

Target

cTnC

Nature

Recombinant

Tag/Conjugate

His

Alternative Names

TNNI3; troponin I type 3 (cardiac); troponin I, cardiac; troponin I, cardiac muscle

Purity

> 85 % as determined by SDS-PAGE

Format

Liquid

Concentration

Batch dependent - please inquire should you have specific requirements

Buffer

PBS

Preservative

None

Storage

Short Term 2-8°C, long term: -20°C

Introduction

Troponin C is a protein which is part of the troponin complex. It contains four calcium-binding EF hands, although different isoforms may have fewer than four functional calcium-binding subdomains. It is a component of thin filaments, along with actin and tropomyosin. It contains an N lobe and a C lobe. The C lobe serves a structural purpose and binds to the N domain of troponin I (TnI). The C lobe can bind either Ca2+ or Mg2+. The N lobe, which binds only Ca2+, is the regulatory lobe and binds to the C domain of troponin I after calcium binding.

Keywords

cTnC; Troponin C; Cardiac