Magic™ Rabbit Anti-Human CCNE1 Monoclonal antibody, clone 351247H0

Antibody Isotype

IgG

Clone

351247H0

Species Reactivity

Human

Immunogen

Cyclin E fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT957 - DMAB-CPT958
Cytometric Bead Array: 0.625-40 ng/mL

General Notes

This product (Catalog No. DMAB-CPT958) is a rabbit-derived monoclonal antibody raised against human CCNE1. It has been affinity purified by Protein A. Cyclin E1 (CCNE1) is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNE1, an essential cyclin activating Cdk2, regulates the G1-S phase transition of the mammalian cell division cycle. Its timing expression plays a direct role in the initiation of DNA replication, the control of histone biosynthesis, and the centrosome cycle. CCNE1 is associated with disease progression in various malignancies and is associated clinically with poor prognosis. Two bands of Cyclin E1 were expressed in U2OS and MDA-MB-231 cells.
DMAB-CPT958 is suitable for use in Cytometric Bead Array (0.625-40 ng/mL) application.
DMAB-CPT958 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

CCNE; CCNE1; cyclin E1; G1/S specific cyclin E1

Entrez Gene ID

UniProt ID