Application: We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT731 - DMAB-CPT732
Summary
Specifications
Antibody Isotype
IgG
Clone
351186G8
Species Reactivity
Human
Immunogen
CBX1 fusion protein
Conjugate
Unconjugated
Applications
Application Notes
We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT731 - DMAB-CPT732
General Notes
This product (Catalog No. DMAB-CPT731) is a rabbit-derived monoclonal antibody raised against human CBX1. It has been affinity purified by Protein A. CBX1, officially known as chromobox 1, is a protein-coding gene in humans that encodes chromobox protein homolog 1 (HP1β), a highly conserved non-histone chromosomal protein belonging to the heterochromatin protein 1 (HP1) family. Located on chromosome 17q21.32, the gene consists of six exons and produces a 185-amino acid protein through alternative splicing variants that yield identical isoforms. This protein is a key component of constitutive heterochromatin, where it associates with centromeres and contributes to the epigenetic control of chromatin structure and gene expression by binding to methylated histone tails and other chromatin-associated factors. DMAB-CPT731 is suitable for use in CBA(Cap), ELISA(Cap) applications. DMAB-CPT731 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
HP1Hs beta; HP1 beta; Heterochromatin protein p25; Chromobox protein homolog 1; CBX1; chromobox 1
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